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Eur J Med Res. 1996 Jan 19;1(4):176-80.

A novel adipocyte long chain fatty acid transport protein.

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  • 1Washington University School of Medicine, 660 South Euclid Avenue, Box 8086, St. Louis, MO 63110, USA.


Uptake of long chain fatty acids (LCFAs) is a critical function of eukaryotic cells. In the past, a diffusional mechanism has been proposed for passage of these hydrophobic molecules across the plasma membrane. I have recently used an expression cloning strategy to identify a novel integral plasma membrane fatty acid transport protein (FATP), which functions as an LCFA transporter. FATP may play a pivotal role in alterations of cellular metabolism which occur in several pathophysiologic states.

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