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1: J Child Neurol. 1997 Aug;12(5):285-300.Click here to read Links

Cerebral hemodynamics and metabolism during infant cardiac surgery. Mechanisms of injury and strategies for protection.

du Plessis AJ.

Department of Neurology, Children's Hospital, Boston, MA 02115, USA.

There is an established link between congenital heart disease and acquired brain injury, which relates to the dependence of the nervous system on a consistent and responsive supply of oxygen and glucose. The advances in the field of infant cardiac surgery have presented new and different challenges to the arena of child neurology. This review provides an overview of the mechanisms of neurologic injury and cerebral hemodynamics and metabolism during cardiac surgery. This review discusses current and future strategies for the management of children with congenital heart disease.

PMID: 9378896 [PubMed - indexed for MEDLINE]