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Ther Drug Monit. 1997 Oct;19(5):543-4.

Quick onset of severe abdominal pain after codeine in an ultrarapid metabolizer of debrisoquine.

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  • 1Department of Medical Laboratory Sciences & Technology, Huddinge University Hospital, Sweden.

Abstract

The authors describe a 33-year-old woman who experienced severe pain in the epigastrium after codeine intake. This side-effect is consistent with that of morphine. Later, the patient was phenotyped and genotyped as an ultrarapid metabolizer with high capacity to metabolize codeine to morphine.

PMID:
9357099
[PubMed - indexed for MEDLINE]
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