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    Psychol Med. 1976 Feb;6(1):59-70.

    The endogenous--neurotic distinction as a predictor of response to antidepressant drugs.

    Abstract

    An inverse factor analysis of 880 depressed inpatients on 33 endogenous-neurotic variables yielded four patient types. Type 3 resembled the endogenous depressions and Type 2 the neurotic depressions. Type 3 patients responded well to both imipramine and chlorpromazine and did poorly on a placebo. Type 2 patients showed the greatest overall improvement at three weeks irrespective of treatment received, including a placebo.

    PMID:
    935298
    [PubMed - indexed for MEDLINE]

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