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1: J Am Acad Dermatol. 1997 Sep;37(3 Pt 2):S59-61.Click here to read Links

Calcipotriol/calcipotriene (Dovonex/Daivonex) in combination with phototherapy: a review.

Koo J.

UCSF Psoriasis and Skin Treatment Center, University of California, San Francisco 94143, USA.

BACKGROUND: Calcipotriol/calcipotriene (Dovonex/Daivonex) ointment plus phototherapy has been used in the treatment of psoriasis. OBJECTIVE: We will attempt to clarify two issues: First, is there any benefit to combining the above treatment modalities? Second, is there any increased risk associated with the use of the combination? METHODS: A complete review of the literature revealed four studies dealing with the combination of calcipotriol with UVB phototherapy and three studies dealing with the combination of calcipotriol with PUVA phototherapy. RESULTS: These studies showed an advantage to the use of the combination compared with the use of either treatment alone. CONCLUSION: Topical calcipotriol enhances the effect of UVB and PUVA phototherapy.

PMID: 9344187 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Calcitriol (Rocaltrol® )

    Calcitriol is a form of vitamin D that is used to treat and prevent low levels of calcium in the blood of patients whose kidneys or parathyroid glands (glands in the neck that release natural substances to control the am...

  • Calcipotriene Topical (Dovonex® )

    Calcipotriene is used to treat psoriasis (a skin disease in which red, scaly patches form due to increased production of skin cells on some areas of the body). Calcipotriene is in a class of medications called synthetic ...

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