Source
UCSF Psoriasis and Skin Treatment Center, University of California, San Francisco 94143, USA.
Abstract
BACKGROUND:
Calcipotriol/calcipotriene (Dovonex/Daivonex) ointment plus phototherapy has been used in the treatment of psoriasis.
OBJECTIVE:
We will attempt to clarify two issues: First, is there any benefit to combining the above treatment modalities? Second, is there any increased risk associated with the use of the combination?
METHODS:
A complete review of the literature revealed four studies dealing with the combination of calcipotriol with UVB phototherapy and three studies dealing with the combination of calcipotriol with PUVA phototherapy.
RESULTS:
These studies showed an advantage to the use of the combination compared with the use of either treatment alone.
CONCLUSION:
Topical calcipotriol enhances the effect of UVB and PUVA phototherapy.