Am J Med Genet. 1997 Oct 31;72(3):339-42.

Familial transmission of a small supernumerary marker chromosome 8 identified by FISH: an update.

Source

Department of Human Genetics, University of Manitoba, Winnipeg, Canada.

Abstract

A father and his 2 daughters were previously determined to carry a small, supernumerary marker chromosome [Chudley et al., 1983]. The origin of this marker could not be determined by standard cytogenetic techniques. In this study, fluorescence in situ hybridization (FISH) studies identified the marker chromosome as a pericentric derivative of chromosome 8. The father has low grade mosaicism for this marker and is phenotypically normal. Both daughters are non-mosaic and show developmental delays and somewhat differing clinical findings. The phenotypes of the 2 sisters are compared with those previously reported for supernumerary der(8) patients. This is the first report of familial transmission of a supernumerary der(8) marker chromosome.

PMID:: 9332666; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Genetic Markers

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Supplemental Content

Save items

Related citations in PubMed

Revaluation twenty-three years later of a supernumerary derivative chromosome 9. [Am J Med Genet. 2002]
Revaluation twenty-three years later of a supernumerary derivative chromosome 9.
Yardin C, Esclaire F, Terro F, Barthe D, Gilbert B. Am J Med Genet. 2002 Aug 1; 111(2):213-4.
Review A series of supernumerary small ring marker autosomes identified by FISH with chromosome probe arrays and literature review excluding chromosome 15. [Am J Med Genet A. 2003]
Review A series of supernumerary small ring marker autosomes identified by FISH with chromosome probe arrays and literature review excluding chromosome 15.
Daniel A, Malafiej P. Am J Med Genet A. 2003 Mar 15; 117A(3):212-22.
Small familial supernumerary ring chromosome 2: FISH characterization and genotype-phenotype correlation. [Am J Med Genet. 2002]
Small familial supernumerary ring chromosome 2: FISH characterization and genotype-phenotype correlation.
Giardino D, Finelli P, Russo S, Gottardi G, Rodeschini O, Atza MG, Natacci F, Larizza L. Am J Med Genet. 2002 Aug 15; 111(3):319-23.
Review SKY assessment of two karyotypes with 0-6 supernumerary marker/ring chromosomes and review of previously reported cases with two or more markers. [Am J Med Genet A. 2003]
Review SKY assessment of two karyotypes with 0-6 supernumerary marker/ring chromosomes and review of previously reported cases with two or more markers.
Reddy KS, Wang S, Groh S, Gonatos J. Am J Med Genet A. 2003 Apr 15; 118A(2):156-71.
Mosaic supernumerary ring chromosome 19 identified by comparative genomic hybridisation. [J Med Genet. 1998]
Mosaic supernumerary ring chromosome 19 identified by comparative genomic hybridisation.
Ghaffari SR, Boyd E, Connor JM, Jones AM, Tolmie JL. J Med Genet. 1998 Oct; 35(10):836-40.

See reviews... See all...

Cited by 1 PubMed Central article

Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements. [Am J Hum Genet. 2001]
Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements.
Giglio S, Broman KW, Matsumoto N, Calvari V, Gimelli G, Neumann T, Ohashi H, Voullaire L, Larizza D, Giorda R, et al. Am J Hum Genet. 2001 Apr; 68(4):874-83. Epub 2001 Feb 26.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Familial transmission of a small supernumerary marker chromosome 8 identified by...
Familial transmission of a small supernumerary marker chromosome 8 identified by FISH: an update.
Am J Med Genet. 1997 Oct 31 ;72(3):339-42.

PubMed
[Normative data on the verbal fluency test in the animal category in our milieu]...
[Normative data on the verbal fluency test in the animal category in our milieu].
Arq Neuropsiquiatr. 1997 Mar ;55(1):56-61.

PubMed
Editorial: 28,000 Gun deaths a year: what is our role?
Editorial: 28,000 Gun deaths a year: what is our role?
J Trauma. 1976 Jun ;16(6):510-1.

PubMed
Effects of silymarin on UDP-glucuronic acid and glucuronidation activity in the ...
Effects of silymarin on UDP-glucuronic acid and glucuronidation activity in the rat isolated hepatocytes and liver in relation to D-galactosamine toxicity.
Indian J Exp Biol. 1997 Mar ;35(3):256-63.

PubMed
Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and...
Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2.
Neuroreport. 1997 Sep 29 ;8(14):3131-5.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: