Alternative splice variants of cytokines: making a...[Life Sci. 1997]

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1: Life Sci. 1997;61(12):1105-12. Links

Alternative splice variants of cytokines: making a list.

Atamas SP.

Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore 21201, U.S.A.

The cytokine network is an extremely complicated and redundant system of mutually interdependent pleiotropic cytokines that interacts with a variety of cells, tissues and organs producing various regulatory effects, both local and systemic. Recent studies have revealed a new source of complexity in the cytokine network--alternative splicing. This minireview attempts to summarize the available data on the alternative splicing of cytokines and its regulatory significance.

PMID: 9315502 [PubMed - indexed for MEDLINE]

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