Nature. 1997 Sep 25;389(6649):349-52.

Histone acetylation in chromatin structure and transcription.

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Department of Biological Chemistry, UCLA School of Medicine and the Molecular Biology Institute, University of California, Los Angeles 90095, USA.

Abstract

'The amino termini of histones extend from the nucleosomal core and are modified by acetyltransferases and deacetylases during the cell cycle. These acetylation patterns may direct histone assembly and help regulate the unfolding and activity of genes.

PMID:: 9311776; [PubMed - indexed for MEDLINE]

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