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Int J Dev Biol. 1997 Aug;41(4):639-42.

Apparent normal phenotype of Fgf6-/- mice.

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  • 1Laboratoire d'Oncologie Mol√©culaire, U119 INSERM, Marseille, France.

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  • Int J Dev Biol 1997 Dec;41(6):following 958.


To study the role of the sixth member of the FGF (fibroblast growth factor) family whose expression is restricted to skeletal muscle, we have derived mouse mutants with a homozygous disruption of the Fgf6 gene. The animals are viable, fertile and apparently normal, indicating that FGF6 is not required for vital functions in the laboratory mouse.

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