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J Comput Assist Tomogr. 1997 Sep-Oct;21(5):756-65.

Comparison between manual and semiautomated analysis of left ventricular volume parameters from short-axis MR images.

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  • 1Laboratory for Clinical and Experimental Image Processing, Leiden University Medical Centre, The Netherlands.

Abstract

PURPOSE:

The goal of this study was to evaluate a newly developed semiautomated contour detection algorithm for the quantitative analysis of cardiovascular MRI.

METHOD:

Left ventricular function parameters derived from automatically detected endocardial and epicardial contours were compared with results derived from manually traced contours in short-axis multislice GRE MRI studies of 10 normal volunteers and 10 infarct patients.

RESULTS:

Compared with manual image analysis, the semiautomated method resulted in the following systematic and random differences (auto-manual; mean +/- SD): end-diastolic volume: -5.5 +/- 9.7 ml; end-systolic volume: -3.6 +/- 6.5 ml; ejection fraction: 1.7 +/- 4.1%; left ventricular mass: 7.3 +/- 20.6 g. Total analysis time for a complete study was reduced from 3-4 h for the manual analysis to < 20 min using semiautomated contour detection.

CONCLUSION:

Global left ventricular function parameters can be obtained with a high degree of accuracy and precision using the present semiautomated contour detection algorithm.

PMID:
9294570
[PubMed - indexed for MEDLINE]
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