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Curr Opin Immunol. 1997 Aug;9(4):528-33.

Protein tyrosine kinases in thymocyte development.

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  • 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5, Canada.


Much has been learned over the past few years about how protein tyrosine kinases mediate pre-TCR and mature alphabetaTCR function. The highlights include understanding the roles and the distinct effects of the Src and Syk families of protein tyrosine kinases in thymocyte development and function.

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