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Curr Opin Nephrol Hypertens. 1997 May;6(3):292-8.

Chimerism after organ transplantation.

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  • 1Pittsburgh Transplantation Institute, Pennsylvania, USA.

Abstract

Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft. Here, we describe how this hematolymphopoietic chimerism provides an important framework for interpretation of post-transplant phenomena and for initiation of therapeutically oriented transplantation research.

PMID:
9263673
[PubMed - indexed for MEDLINE]
PMCID:
PMC2955429
Free PMC Article

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