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Eur J Gastroenterol Hepatol. 1997 Jul;9(7):655-6.

Endomysium: autoantigen in coeliac disease.

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  • 1Department of Immunology, Trinity College, Dublin, Ireland.

Abstract

In coeliac disease, dietary exposure to gluten is associated with an autoimmune response to gastrointestinal antigens, including endomysium. Measurement of autoantibodies to endomysium is a highly specific and sensitive method of diagnosing coeliac disease. Analysis of the interaction between gluten and endomysium should provide a critical insight into the pathogenesis of this condition.

PMID:
9262971
[PubMed - indexed for MEDLINE]
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