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Structure. 1997 Jun 15;5(6):729-34.

A biopolymer by any other name would bind as well: a comparison of the ligand-binding pockets of nucleic acids and proteins.

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  • 1Department of Chemistry, Indiana University, Bloomington 47405, USA.

Abstract

Crystal structures have recently been reported for several in vitro selected aptamers that bind small molecules. A structural comparison of these aptamers with proteins that bind identical ligands reveals similar strategies for forming ligand-binding pockets.

PMID:
9261068
[PubMed - indexed for MEDLINE]
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