Cephalalgia. 1997 Aug;17(5):596-9.

Prophylactic treatment of migraine with bisoprolol: a placebo-controlled study.

Source

E. Merck Nederland b.v. Amsterdam, The Netherlands.

Abstract

The objective of the present study was to assess the efficacy of bisoprolol in migraine prophylaxis. A double-blind placebo-controlled study was conducted in 226 patients with migraine with or without aura, a migraine history of at least 2 years at least 3 documented attacks during the 28 days run-in period. The duration of treatment was 12 weeks following an initial 28 days' run-in period. Patients reported the number of attacks and their severity in a diary. Treatment with bisoprolol 5 mg resulted in a significant reduction in the frequency of migraine attacks (39% vs 22%) compared to placebo treatment (p < 0.05). Treatment had no effect on the duration and severity of the attacks. Bisoprolol was well tolerated.

PMID:: 9251876; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis--a double-blind, multicentre, randomized placebo-controlled dose-response study. [Cephalalgia. 2002]
The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis--a double-blind, multicentre, randomized placebo-controlled dose-response study.
Pfaffenrath V, Diener HC, Fischer M, Friede M, Henneicke-von Zepelin HH, Investigators. Cephalalgia. 2002 Sep; 22(7):523-32.
[Prevention of migraine using bisoprolol. Results of a double-blind study versus metoprolol]. [Fortschr Med. 1992]
[Prevention of migraine using bisoprolol. Results of a double-blind study versus metoprolol].
Wörz R, Reinhardt-Benmalek B, Föh M, Grotemeyer KH, Scharafinski HW. Fortschr Med. 1992 May 20; 110(14):268-72.
Cyclandelate in the prophylaxis of migraine: a placebo-controlled study. [Cephalalgia. 2001]
Cyclandelate in the prophylaxis of migraine: a placebo-controlled study.
Diener HC, Krupp P, Schmitt T, Steitz G, Milde K, Freytag S. Cephalalgia. 2001 Feb; 21(1):66-70.
Review Beta-adrenoceptor blockers and calcium antagonists in the prophylaxis and treatment of migraine. [Drugs. 1990]
Review Beta-adrenoceptor blockers and calcium antagonists in the prophylaxis and treatment of migraine.
Andersson KE, Vinge E. Drugs. 1990 Mar; 39(3):355-73.
Review [A review of the pharmacologic treatment of migraine in children]. [Rev Neurol. 2003]
Review [A review of the pharmacologic treatment of migraine in children].
Vasconcellos E. Rev Neurol. 2003 Aug 1-15; 37(3):253-9.

See reviews... See all...

Cited by 2 PubMed Central articles

The pharmacological management of migraine, part 2: preventative therapy. [P T. 2008]
The pharmacological management of migraine, part 2: preventative therapy.
Demaagd G. P T. 2008 Aug; 33(8):480-7.
Review The prevention of migraine: a critical review with special emphasis on beta-adrenoceptor blockers. [Br J Clin Pharmacol. 2001]
Review The prevention of migraine: a critical review with special emphasis on beta-adrenoceptor blockers.
Limmroth V, Michel MC. Br J Clin Pharmacol. 2001 Sep; 52(3):237-43.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Prophylactic treatment of migraine with bisoprolol: a placebo-controlled study.
Prophylactic treatment of migraine with bisoprolol: a placebo-controlled study.
Cephalalgia. 1997 Aug ;17(5):596-9.

PubMed
Increased LH and FSH secretion after cranial irradiation in boys.
Increased LH and FSH secretion after cranial irradiation in boys.
Med Pediatr Oncol. 1997 Oct ;29(4):280-7.

PubMed
Demographic and clinical characteristics as predictors of length of hospitalizat...
Demographic and clinical characteristics as predictors of length of hospitalization and readmission.
J Clin Psychol. 1977 Oct ;33(4):1093-9.

PubMed
Language bias in randomised controlled trials published in English and German.
Language bias in randomised controlled trials published in English and German.
Lancet. 1997 Aug 2 ;350(9074):326-9.

PubMed
Early radiological observations may predict the long-term survival of femoral hi...
Early radiological observations may predict the long-term survival of femoral hip prostheses.
J Bone Joint Surg Br. 1997 Jul ;79(4):583-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: