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Int J Radiat Oncol Biol Phys. 1997 Jul 1;38(4):891-7.

Phantom assessment of lung dose from proton arc therapy.

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  • 1Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, USA.

Abstract

PURPOSE:

To compare resultant lung dose from proton arc therapy of the chest wall to that from electron arc therapy.

METHODS AND MATERIALS:

A 200 MeV proton beam from the Indiana University Cyclotron was range shifted and modulated to provide a spread out Bragg peak extending from the surface to a depth of 4 cm in water. The chest wall of an Alderson Rando phantom was irradiated by this beam, collimated to a 20 x 4 cm field size, while it rotated on a platform at approximately 1 rpm. For comparison, electron arc therapy of the Rando phantom chest wall was similarly performed with 12 MeV electrons and the resultant lung dose measured in each case.

RESULTS:

Dose-volume histograms for the Rando phantom left lung indicate a reduced volume of irradiated lung for protons at all dose levels and an integral lung dose that is half that for electron arc therapy in the case studied. In addition, a more uniform dose coverage of the target volume was achieved with the proton therapy.

CONCLUSION:

This study demonstrates a potential role for proton arc therapy as an alternative to electron arc therapy when lung dose must be minimized.

PMID:
9240659
[PubMed - indexed for MEDLINE]
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