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1: Dermatol Clin. 1996 Oct;14(4):803-11.Links

Antiandrogen and hormonal treatment of acne.

Shaw JC.

Department of Dermatology, Oregon Health Sciences University, Portland, USA.

In the treatment of acne in women, the use of antiandrogens and other hormonal approaches is a valuable alternative to standard therapy. These treatments that are based on physiologically sound principles produce gratifying results in selected women with acne, and are the primary treatment for women with hirsutism. The drugs discussed in this article include spironolactone, cyproterone acetate, flutamide, oral contraceptives, corticosteroids, finasteride, and gonadotropin-releasing hormone agonists. Patient selection, pretreatment evaluation, and case studies also are discussed with an emphasis on practical applications.

PMID: 9238337 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Spironolactone (Aldactone® )

    Spironolactone is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; and in patients with edema (fluid retention) caused ...

  • Flutamide

    Flutamide is used together with a luteinizing hormone-releasing hormone agonist (LHRH; a type of hormonal injection such as leuprolide [Lupron, Eligard], goserelin [Zoladex], or triptorelin [Trelstar]) to treat certain t...

  • Finasteride (Proscar® , Propecia® )

    Finasteride (Proscar) is used alone or in combination with another medication (doxazosin [Cardura]) to treat benign prostatic hypertrophy (BPH, enlargement of the prostate gland). Finasteride improves symptoms of BPH suc...

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