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Int J Cancer. 1997 Jul 3;72(1):62-7.

A case-control study of self-reported exposures to pesticides and pancreas cancer in southeastern Michigan.

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  • 1Department of Preventive and Societal Medicine, University of Nebraska Medical Center, Omaha 68198-4350, USA. jfryzek@mail.unmc.edu

Abstract

A case-control study of pancreas cancer in residents, aged 30-79 years, of 18 counties in southeastern Michigan was conducted to investigate the risks of exposure to DDT and related materials in the general population. Sixty-six people with cytologically diagnosed pancreas cancer were identified using 7 participating hospitals in metropolitan Detroit and Ann Arbor. One hundred and thirty-one controls were frequency-matched to the cases on age, sex, ethicity and county of residence by random-digit dialing. All study participants were administered a questionnaire to assess life-time exposure to pesticides from both environmental and occupational sources, family history of cancer, past medical history, smoking history and demographic information. A statistically significant increased risk was found for self-reported exposure to ethylan (1,1-dichloro-2,2-bis(4-methoxyphenyl) ethane). Increased odds ratios were observed for self-reported exposures to chloropropylate and DDT, as well as for the summary group of organochlorine pesticides which included all of these materials, though these associations were not significant.

PMID:
9212224
[PubMed - indexed for MEDLINE]
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