FasL--too much of a good thing? Transplanted grafts of pancreatic islet cells engineered to express Fas ligand are destroyed not protected by the immune system

Nat Med. 1997 Jul;3(7):727-8. doi: 10.1038/nm0797-727.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Cell Transplantation
  • Diabetes Mellitus, Experimental / immunology
  • Fas Ligand Protein
  • Genetic Engineering
  • Islets of Langerhans / cytology
  • Islets of Langerhans / immunology*
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / immunology*
  • Mice
  • Mice, Transgenic
  • Neutrophils / immunology
  • Transplantation Immunology*

Substances

  • Fas Ligand Protein
  • Fasl protein, mouse
  • Membrane Glycoproteins