Ann Intern Med. 1977 Nov;87(5):568-70.

Prolonged colchicine treatment in four patients with amyloidosis.

Abstract

The natural clinical course of four patients with systemic amyloidosis was favourably altered by continuous colchicine therapy. One patient had primary amyloidosis, and the other three suffered from amyloidosis of familial Mediterranean fever. All had a nephrotic syndrome, and one showed features of intestinal malabsorption. The institution of colchicine therapy was followed by a gradual remission of the nephrotic syndrome, a rise of serum albumin to normal values, a slight improvement of renal function, and regression of the intestinal malabsorption. This pattern has remained steady during an observation period of 30 months.

PMID:: 921085; [PubMed - indexed for MEDLINE]

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[Nephrotic syndrome in familial Mediterranean fever--effect of colchicine therapy]. [Ugeskr Laeger. 1995]
[Nephrotic syndrome in familial Mediterranean fever--effect of colchicine therapy].
Højberg AS, Mertz H. Ugeskr Laeger. 1995 Jul 10; 157(28):4035-7.
[Regression of nephrotic syndrome in amyloidosis secondary to familial Mediterranean fever during maintenance therapy using colchicine]. [Med Clin (Barc). 1989]
[Regression of nephrotic syndrome in amyloidosis secondary to familial Mediterranean fever during maintenance therapy using colchicine].
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Review [From familial Mediterranean fever to amyloidosis].
Vinceneux P, Pouchot J. Presse Med. 2005 Jul 23; 34(13):958-66.

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Cited by 15 PubMed Central articles

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Review Amyloidosis.
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