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J Pediatr Hematol Oncol. 1997 May-Jun;19(3):247-50.

Preoperative chemotherapy for congenital hemangiopericytoma and a review of the literature.

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  • 1Division of Pediatric Hematology/Oncology, University of Florida Health Science Center, Gainesville, USA.

Abstract

PURPOSE:

Malignant hemangiopericytoma is an uncommon tumor in the pediatric age group. A case of congenital hemangiopericytoma is presented with a review of the literature.

PATIENTS AND METHODS:

A 2-month-old boy presented at birth with an enlarging posterior neck mass. Subsequent histopathologic studies showed findings consistent with hemangiopericytoma. Imaging studies demonstrated an extensive, infiltrative, vascular lesion not readily amenable to surgical resection. A pulmonary metastatic lesion was present.

RESULTS:

Combined treatment using vincristine, doxorubicin, and cyclophosphamide given preoperatively resulted in a significant decrease in size of the primary tumor, allowing for resection without complication and resolution of the metastatic lesion.

CONCLUSION:

Preoperative chemotherapy may have a significant role in the management of infants with malignant hemangiopericytoma.

PMID:
9201149
[PubMed - indexed for MEDLINE]
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