J Clin Microbiol. 1997 Jul;35(7):1791-3.

Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR.

Pitkäranta A, Arruda E, Malmberg H, Hayden FG.

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Department of Internal Medicine, University of Virginia, Charlottesville 22908, USA.

Abstract

Of 20 adults with acute community-acquired sinusitis (ACAS), rhinovirus was detected in specimens from 10 (50%) patients, including maxillary aspirates from 8 (40%) patients and nasal swabs from 9 (45%) patients, by reverse transcription-PCR (RT-PCR). Human coronavirus was detected by RT-PCR in nasal swabs from 3 of 20 patients but in no sinus secretions. These findings suggest that rhinovirus is an important cause of ACAS and that viral invasion of the sinus cavity itself may be a common event during the disease.

PMID:: 9196195; [PubMed - indexed for MEDLINE]
PMCID:: PMC229843

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