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Gen Pharmacol. 1997 Jul;29(1):7-15.

In vivo neuropharmacological and in vitro laser ablation techniques as tools in the analysis of neuronal circuits underlying behavior in a molluscan model system.

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  • 1Sussex Centre for Neuroscience, School of Biology, University of Sussex, Falmer, Brighton, United Kingdom.


1. This paper reviews the selective lesioning techniques employed to elucidate the role of the neurotransmitters dopamine and serotonin and single, identified interneurons in the feeding system of the pond snail Lymnaea stagnalis. 2. The pathway lesioning work reviewed in this paper showed that dopamine is necessary for the feeding response to occur and serotonin has a mainly modulatory role in the feeding system of Lymnaea. 3. The photoinactivation results reviewed here assist in the elucidation of the different roles that different types of interneurons play in the initiation and modulation of patterned neuronal activity underlying feeding.

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