The serum-IgE (sIgE) levels of eight patients with cataract complicated by atopic dermatitis (atopic cataract) who had undergone cataract surgery were reported. Five of them were diagnosed as having cataract the first visit to our eye clinic. The other three cases did not show cataract at the first visit but developed it later. The average sIgE of the five cases with cataract was 25,478 +/- 15,936 (mean +/- standard deviation) iu/ml whereas that of the latter three cases without cataract, at the first visit was 4,638 +/- 1,810 iu/ml. The average sIgE of these three cases when their cataracts were diagnosed first went up to 13,210 +/- 5,574 iu/ml. These results suggested that a high level of sIgE may be a warning of the appearance of atopic cataract.