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HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors.
Ambrosino C, Ruocco MR, Chen X, Mallardo M, Baudi F, Trematerra S, Quinto I, Venuta S, Scala G.
J Biol Chem. 1997 Jun 6;272(23):14883-92.
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The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein.
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