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World J Urol. 1997;15(2):84-8.

Natural history of superficial bladder tumors: 10- to 20-year follow-up of treated patients.

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  • 1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.


Superficial bladder tumors (Ta, Tl, Tis) account for 80% of primary bladder cancers. Transurethral resection and intravesical therapy are successful in controlling the majority of these tumors for up to 5 years. However, patients with multiple or recurrent Ta, Tl and Tis bladder cancer have a lifelong risk of developing stage progression and upper tract tumors. One-half are at risk of having cystectomy eventually and one-third are at risk over a 15-20 year period of dying of bladder cancer.

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