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J Neuropsychiatry Clin Neurosci. 1997 Spring;9(2):277-9.

AIDS mania.

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  • 1AIDS Psychiatry Service and Neuropsychiatry and Memory Group, Johns Hopkins University, Baltimore, Maryland 21287, USA.


Twenty patients with HIV infection and mania were grouped according to whether their first manic episode occurred when CD4 count was < 200 (late onset) or > or = 200 (early onset). The late-onset patients were less likely to have personal or family histories of mood disorder and more likely to have dementia or cognitive slowing. They also exhibited a different manic symptom profile. The different sociodemographic and symptom profiles associated with early-onset and late-onset mania may reflect differences in pathophysiology.

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