Your browser version may not work well with NCBI's Web applications. More information here...
1: J Nat Prod. 1997 Apr;60(4):417-8.Click here to read Links

Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens).

Shimada H, Tyler VE, McLaughlin JL.

Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, USA.

Brine shrimp lethality-directed fractionation of the 95% EtOH extract of the powdered, dried berries of Serenoa repens (Bart.) Small (saw-palmetto) (Palmae) led to the isolation of two monoacylglycerides, 1-monolaurin (1) and 1-monomyristin (2). Compounds 1 and 2 showed moderate biological activities in the brine shrimp lethality test and against renal (A-498) and pancreatic (PACA-2) human tumor cells; borderline cytotoxicity was exhibited against human prostatic (PC-3) cells. The fruits and extracts of saw-palmetto are taken orally as an herbal medicine to prevent prostatic hyperplasias.

PMID: 9134750 [PubMed - indexed for MEDLINE]