Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Biochem Biophys Res Commun. 1997 Mar 27;232(3):728-30.

Association of a genetic variation in the beta 3-adrenergic receptor gene with coronary heart disease among Japanese.

Author information

  • 1First Department of Internal Medicine, National Defense Medical College, Saitama, Japan.

Abstract

Mutation frequencies in the beta 3-adrenergic receptor gene were measured in 83 CAD patients and 107 controls (all Japanese nationals) and the mutation incidence in the two groups was compared. The relationship between characteristics of lipid and glucose metabolism and presence or absence of the mutation was examined in CAD patients. The frequency of this mutant allele in CAD patients was significantly higher than that of controls. The presence of this mutation was significantly associated with higher body mass index, but not with other plasma lipid and glucose levels in CAD patients. This mutation was associated with coronary heart disease and obesity but was not with glucose and lipid metabolism disorders in Japanese nationals.

PMID:
9126344
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk