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    Neurol Clin. 1997 May;15(2):299-308.

    Tourette syndrome. Coprolalia and other coprophenomena.

    Singer C.

    Movement Disorders Clinic, Department of Neurology, University of Miami School of Medicine, Miami, Florida 33136, USA.

    Coprolalia has been a recognized symptom of Tourette syndrome from the first description of the syndrome. Copropraxia is seen less frequently and almost always occurs in association with coprolalia. Prevalence of coprolalia varies from 8% in primary pediatric practices to over 60% in tertiary referral centers. Coprolalia tends to peak in severity during adolescence and to wane during adulthood. The pathogenesis may be related to dysfunction of basal ganglionic and limbic mini-circuits. Coprolalia has also been seen in a variety of other neurologic disorders. Treatment is primarily pharmacologic with dopamine-blocking agents.

    PMID: 9115463 [PubMed - indexed for MEDLINE]

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