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Epidemiology. 1997 May;8(3):293-7.

The role of passive smoking in the development of bronchial obstruction during the first 2 years of life.

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  • 1Department of Population Health Sciences, National Institute of Public Health, Oslo, Norway.

Abstract

We assessed the effect of exposure to environmental tobacco smoke on the risk of developing bronchial obstruction in a 2-year cohort study of 3,754 children born in Oslo, Norway, during a period of 15 months in 1992-1993. We collected questionnaire information on the child's health and environmental exposures at birth and when the child was age 6 months (follow up rate = 95%), 12 months (92%), 18 months (92%), and 24 months (81%). The outcome of interest was defined as two or more episodes of bronchial obstruction or one obstruction lasting more than 1 month, and it was verified by a specialist group evaluating data from questionnaires, clinical examinations, and health records. The risk of bronchial obstruction was increased in children exposed to environmental tobacco smoke (cumulative incidence = 0.109) compared with unexposed children (0.071), with an adjusted odds ratio of 1.6 [95% confidence interval (CI) = 1.3-2.1]. The effect was seen for maternal smoking alone (odds ratio = 1.6; 95% CI = 1.0-2.6), paternal smoking alone (odds ratio = 1.5; 95% CI = 1.1-2.2), and both parents smoking (odds ratio = 1.5; 95% CI = 1.0-2.2). There was no clear exposure-response pattern. The findings indicate that exposure to environmental tobacco smoke such as is experienced in Norwegian housing increases the risk of developing bronchial obstruction during the first 2 years of life.

PMID:
9115025
[PubMed - indexed for MEDLINE]
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