Hemodynamic, electrocardiographic, metabolic, and hematologic abnormalities resulting from lithium intoxication. A case report

Angiology. 1997 Apr;48(4):351-4. doi: 10.1177/000331979704800408.

Abstract

The authors report a unique case that presented with hemodynamic abnormalities and severe bradycardia, necessitating the insertion of a temporary pacemaker, as well as metabolic disturbances, hematologic changes, and hepatic and renal dysfunction in an elderly individual owing to lithium intoxication. This case also demonstrates that these various serious side effects of lithium resolved with prompt recognition and discontinuation of lithium. Lithium should be used with extreme caution and frequent monitoring especially in the elderly.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antimanic Agents / poisoning*
  • Antimanic Agents / therapeutic use
  • Atrial Fibrillation / complications
  • Bipolar Disorder / complications
  • Bipolar Disorder / drug therapy
  • Bradycardia / chemically induced
  • Bradycardia / therapy
  • Chemical and Drug Induced Liver Injury
  • Electrocardiography
  • Female
  • Humans
  • Hypotension / chemically induced
  • Kidney Diseases / chemically induced
  • Leukocytosis / chemically induced
  • Lithium Carbonate / poisoning*
  • Lithium Carbonate / therapeutic use
  • Pacemaker, Artificial
  • Water-Electrolyte Imbalance / chemically induced

Substances

  • Antimanic Agents
  • Lithium Carbonate