Acta Otolaryngol Suppl. 1997;526:43-6.

Physiopathology of H3-receptors and pharmacology of betahistine.

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Department of Otorhinolaryngology, University Hospital of Ghent, Belgium.

Abstract

This article reviews published research on the physiology of histamine H3-receptors. The function of this inhibitory autoreceptor, its localisation and influence on histaminergic neurones as well as histamine-controlled processes are presented together with the role of H3-receptors in the vestibular system. In addition to a summary of the properties of the main H3-agonists and -antagonists, the pharmacology of betahistine and its place in the treatment of vertigo are discussed.

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Physiopathology of H3-receptors and pharmacology of betahistine.

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Cited by 3 PubMed Central articles

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