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    J Am Acad Dermatol. 1997 Apr;36(4):531-7.

    Thyroid carcinoma metastatic to the skin: a cutaneous manifestation of a widely disseminated malignancy.

    Dahl PR, Brodland DG, Goellner JR, Hay ID.

    Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

    BACKGROUND: Cutaneous metastases develop in 2% to 9% of patients with an internal malignancy. Thyroid carcinoma metastatic to the skin is a rare clinical entity. OBJECTIVE: Our purpose was to study the clinical and pathologic features and outcome in patients with cutaneous metastasis from thyroid carcinoma. METHODS: The study included a retrospective analysis of six patients with skin metastases from thyroid carcinoma and a review of the English-language literature since 1964. RESULTS: Including our six patients, 43 patients with skin metastases from thyroid carcinoma have been reported. Papillary carcinoma was the most common (41%), followed by follicular (28%), anaplastic (15%), and medullary carcinomas (15%). The scalp was the most common site of metastasis. For our patients, the average length of survival after diagnosis of cutaneous metastasis was 19 months. CONCLUSION: Cutaneous metastasis from thyroid carcinoma is rare and occurs in the setting of disseminated neoplastic disease.

    PMID: 9092737 [PubMed - indexed for MEDLINE]

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