Format

Send to:

Choose Destination
See comment in PubMed Commons below
Br J Obstet Gynaecol. 1997 Mar;104(3):336-9.

Use of oral misoprostol in the prevention of postpartum haemorrhage.

Author information

  • 1Department of Obstetrics and Gynaecology, University College Hospital, London, UK.

Abstract

OBJECTIVE:

To investigate the use of the oral prostaglandin E1 analogue, misoprostol in the prevention of postpartum haemorrhage.

DESIGN:

A prospective observational study.

SETTING:

A university teaching hospital.

PARTICIPANTS:

Two hundred and thirty-seven consecutive women undergoing vaginal delivery.

METHODS:

All the women were given 600 micrograms oral misoprostol just after delivery.

MAIN OUTCOME MEASURES:

Rates of postpartum haemorrhage; need for therapeutic oxytocic drugs; retained placenta and length of the third stage of labour.

RESULTS:

Postpartum haemorrhage occurred in 6% of the women; the need for therapeutic oxytocics in 5%, retained placenta in 2% and the median length of the third stage was 5 min. Vomiting and diarrhoea in the first hour after delivery occurred in 8% and 3% respectively and shivering in 60%.

CONCLUSIONS:

Misoprostol may be effective in the prevention of postpartum haemorrhage, and has few side effects. A double blind randomised trial is required.

Comment in

PMID:
9091012
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk