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J Intellect Disabil Res. 1997 Feb;41 ( Pt 1):87-91.

Autism in Down's syndrome: family history correlates.

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  • 1Taubman Centre, University of Michigan Medical Centre, Ann Arbor 48109-0390, USA.


Although the association of autism with Down's syndrome is said to be uncommon, several reports have described the co-occurrence of the two disorders. This report describes three additional cases of Down's syndrome with autism. In all the patients, a history suggestive of the broader phenotype of autism was obtained in parents. This suggests that familial factors specific to autism may play an important role even when autism complicates a known medical condition such as Down's syndrome.

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