Format

Send to

Choose Destination
See comment in PubMed Commons below
Radiology. 1997 Mar;202(3):697-702.

Detection of extracapsular extension of prostate carcinoma with endorectal and phased-array coil MR imaging: multivariate feature analysis.

Author information

  • 1Department of Radiology, University of California, San Francisco 94143, USA.

Abstract

PURPOSE:

To determine which magnetic resonance (MR) imaging features are most predictive of extracapsular extension of prostate carcinoma.

MATERIALS AND METHODS:

In 77 patients who had stage pT2 or pT3 prostate carcinoma, MR images were retrospectively reviewed by three readers with varying experience in interpretation of endorectal coil images of the prostate gland. MR imaging features assessed were broad tumor contact, smooth capsular bulge, irregular bulge, obliteration of the rectoprostatic angle, and asymmetry of the neurovascular bundle. Multivariate logistic regression analysis was performed to determine the relative value of each MR imaging feature.

RESULTS:

At multivariate analysis, obliteration of the rectoprostatic angle and asymmetry of the neurovascular bundle were most predictive of extracapsular extension, with a specificity of up to 95% and sensitivity of 38%. Poor-quality images reduced accuracy for all readers. The most experienced reader demonstrated overall accuracy of 77% in determination of extracapsular extension.

CONCLUSION:

Obliteration of the rectoprostatic angle and asymmetry of the neurovascular bundle were most indicative of extracapsular extension. Reader experience plays an important role in the ability to interpret prostate MR images and is an important contributor to interobserver variability.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Write to the Help Desk