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Curr Opin Struct Biol. 1997 Feb;7(1):103-9.

DNA-repair enzymes.

Author information

  • 1International Institute for Advanced Research, Central Research Laboratories, Matsushita Electric Industrial, 3-4 Hikari-dai, Seika, Kyoto 619-02, Japan. dmitry@crl.mei.co.jp

Abstract

Recent crystallographic studies of DNA-repair enzymes have provided the structural basis for the recognition of damaged DNA. The results imply that flipping out of the base is a common and crucial event in DNA repair. Two classes of repair enzymes that recognize distinct types of damage may exist. DNA-repair enzymes that share similar folds and DNA binding motifs have been proposed to belong to a superfamily.

PMID:
9032058
[PubMed - indexed for MEDLINE]
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