Chem Pharm Bull (Tokyo). 1996 Feb;44(2):333-6.

Pharmacologically active components of a Peruvian medicinal plant, huanarpo (Jatropha cilliata).

Okuyama E, Okamoto Y, Yamazaki M, Satake M.

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Faculty of Pharmaceutical Sciences, Chiba University, Japan.

Abstract

From Jatropha cilliata M. Arg., a Peruvian medicinal plant, isoorientin and orientin were isolated as anxiolytic components by using the isolation guide of anti-conflict effect in mice. Several related flavonoids were also tested for this effect. Another bioassay-guided isolation using the acetic acid-induced writhing method gave a coumarin compound, fraxetin, as an analgesic principle.

PMID:: 8998840; [PubMed - indexed for MEDLINE]

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