Magn Reson Med. 1996 Apr;35(4):606-10.

Reproducibility of high spatial resolution proton magnetic resonance spectroscopic imaging in the human brain.

Charles HC, Lazeyras F, Tupler LA, Krishnan KR.

Source

Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Abstract

The application of proton (1H) magnetic resonance spectroscopic imaging (MRSI) allows for noninvasive, localized analyses of brain biochemistry; however, minimal work has been devoted to the evaluation of 1H MRSI reproducibility. This study examined the reproducibility of 1H MRSI from five normal subjects on two occasions, separated by 10 days. Reproducibility of the MR signal was evaluated in the context of automated shimming, automated processing, and accurate subject repositioning. Reliability measures for physicochemical indices (choline moieties, creatine, N-acetylaspartate, and myo-inositol) were moderately concordant across repeat studies. Gain variation and repositioning results were excellent. It has been concluded that 1H MRSI reproducibility is adequate for serial studies of brain metabolism.

PMID:: 8992213; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

Protons

LinkOut - more resources

Full Text Sources

OhioLINK Electronic Journal Center

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Fast method for brain image segmentation: application to proton magnetic resonance spectroscopic imaging. [Magn Reson Med. 2005]
Fast method for brain image segmentation: application to proton magnetic resonance spectroscopic imaging.
Bonekamp D, Horská A, Jacobs MA, Arslanoglu A, Barker PB. Magn Reson Med. 2005 Nov; 54(5):1268-72.
Short echo time 1H MRSI of the human brain at 3T with adiabatic slice-selective refocusing pulses; reproducibility and variance in a dual center setting. [J Magn Reson Imaging. 2010]
Short echo time 1H MRSI of the human brain at 3T with adiabatic slice-selective refocusing pulses; reproducibility and variance in a dual center setting.
Wijnen JP, van Asten JJ, Klomp DW, Sjobakk TE, Gribbestad IS, Scheenen TW, Heerschap A. J Magn Reson Imaging. 2010 Jan; 31(1):61-70.
Brain regional distribution pattern of metabolite signal intensities in young adults by proton magnetic resonance spectroscopic imaging. [Neurology. 1995]
Brain regional distribution pattern of metabolite signal intensities in young adults by proton magnetic resonance spectroscopic imaging.
Tedeschi G, Bertolino A, Righini A, Campbell G, Raman R, Duyn JH, Moonen CT, Alger JR, Di Chiro G. Neurology. 1995 Jul; 45(7):1384-91.
Review Proton magnetic resonance spectroscopy imaging in the study of human brain cancer. [Q J Nucl Med Mol Imaging. 2009]
Review Proton magnetic resonance spectroscopy imaging in the study of human brain cancer.
Martínez-Bisbal MC, Celda B. Q J Nucl Med Mol Imaging. 2009 Dec; 53(6):618-30.
Review Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy. [Pediatr Neurol. 2009]
Review Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy.
Brighina E, Bresolin N, Pardi G, Rango M. Pediatr Neurol. 2009 May; 40(5):327-42.

See reviews... See all...

Cited by 1 PubMed Central article

Early detection and longitudinal changes in amyotrophic lateral sclerosis by (1)H MRSI. [Neurology. 2002]
Early detection and longitudinal changes in amyotrophic lateral sclerosis by (1)H MRSI.
Suhy J, Miller RG, Rule R, Schuff N, Licht J, Dronsky V, Gelinas D, Maudsley AA, Weiner MW. Neurology. 2002 Mar 12; 58(5):773-9.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Reproducibility of high spatial resolution proton magnetic resonance spectroscop...
Reproducibility of high spatial resolution proton magnetic resonance spectroscopic imaging in the human brain.
Magn Reson Med. 1996 Apr ;35(4):606-10.

PubMed
How to apply Larsen score in evaluating radiographs of rheumatoid arthritis in l...
How to apply Larsen score in evaluating radiographs of rheumatoid arthritis in long-term studies.
J Rheumatol. 1995 Oct ;22(10):1974-5.

PubMed
Meta-analytic evaluation of skills training research for individuals with severe...
Meta-analytic evaluation of skills training research for individuals with severe mental illness.
J Consult Clin Psychol. 1996 Dec ;64(6):1337-46.

PubMed
Consumer's information needs: results of a national survey.
Consumer's information needs: results of a national survey.
Health Aff (Millwood). 1996 Winter ;15(4):31-41.

PubMed
The power of placebo.
The power of placebo.
BMJ. 1996 Dec 21-28 ;313(7072):1569-70.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: