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J Pediatr Psychol. 1996 Dec;21(6):833-40.

Effect of prenatal alcohol and cigarette exposure on two- and six-month-old infants' adrenocortical reactivity to stress.

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  • 1Institute for the Study of Child Development, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903-0019, USA.


Examined the effect of prenatal alcohol and cigarette exposure on infant adrenocortical reactivity to stress at 2 and 6 months of age. Cortisol response (pre- to poststressor increase) at 2 months was lower for the exposed than nonexposed infants, whereas cortisol response at 6 months did not differ between the exposed and nonexposed infants. The 2-month group difference in cortisol response reflected a higher prestressor cortisol level in the exposed infants.

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