Send to:

Choose Destination
See comment in PubMed Commons below
J Am Vet Med Assoc. 1997 Jan 1;210(1):51-4.

Malignant hyperthermia-like reaction secondary to ingestion of hops in five dogs.

Author information

  • 1National Animal Poison Control Center (presently the ASPCA National Animal Poison Control Center), College of Veterinary Medicine, University of Illinois, Urbana 61801, USA.


Five dogs, 4 of which were Greyhounds, suffered adverse effects secondary to the ingestion of spent hops. Mean time to onset of clinical signs was 3 hours, and clinical signs included marked hyperthermia, restlessness, panting, vomiting, signs of abdominal pain, and seizures. Four of the 5 dogs died despite aggressive therapeutic measures, and there was rapid onset of rigor mortis in 3. The overrepresentation of Greyhounds, coupled with the clinical signs, was suggestive of a malignant hyperthermia-like response to the ingestion of hops. It also is possible that hops contain an uncoupler of oxidative phosphorylation.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk