Semin Pediatr Neurol. 1996 Dec;3(4):260-9.

Subacute sclerosing panencephalitis.

Source

Department of Neurology, Brown University, Rhode Island Hospital, Providence, USA.

Abstract

Subacute sclerosing panencephalitis (SSPE), a neurodegenerative disease caused by a persistent "slow virus infection" with a mutated measles virus, is endemic in much of the developing world. Its incidence will increase in the USA, not only in immigrants, but also because of the 1988-1990 measles epidemic. This report reviews the pathogenesis, clinical and laboratory diagnosis, and future perspectives in treatment and prevention.

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Review

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Interferon-alpha

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