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Urol Clin North Am. 1996 Nov;23(4):633-50.

Should brachytherapy be considered a therapeutic option in localized prostate cancer?

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  • 1Northwest Tumor Institute, University of Washington School of Medicine, Seattle, USA.


Contemporary prostate brachytherapy incorporates advances in computer analysis, imaging technology, and delivery apparatus, allowing exacting and reproducible results compared with historical approaches. The advances permit brachytherapy to be performed on a cost-effective, outpatient basis with low morbidity in the appropriately selected patient. Although unsettled questions remain regarding dosimetric issues, long-term outcomes, and morbidity, the weight of evidence to date appears to support the use of brachytherapy in selected patients. Brachytherapy may be considered a therapeutic option: as monotherapy for early-stage disease and also a boost following moderate doses of external beam irradiation for locally advanced disease.

[PubMed - indexed for MEDLINE]
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