Long-term effects of antineoplastic chemotherapy and radiotherapy on dental development

Dent Update. 1996 Jun;23(5):188-94.

Abstract

Advances in treatment protocols over the past 20 years have resulted in much improved survival rates for children with cancer. As more children survive, the emphasis has moved from "saving children at all costs' to saving children "at least cost to the child' and protocols are continually reviewed with this in mind. As more dental practitioners are likely to encounter children who have survived malignant disease, this paper looks at the long-term effects of treatment modalities on the dentoalveolar complex.

MeSH terms

  • Adolescent
  • Antineoplastic Agents / adverse effects*
  • Child
  • Child, Preschool
  • Cranial Irradiation / adverse effects*
  • Head and Neck Neoplasms / drug therapy
  • Head and Neck Neoplasms / radiotherapy
  • Humans
  • Maxillofacial Development / drug effects
  • Maxillofacial Development / radiation effects
  • Mouth Diseases / etiology
  • Odontogenesis / drug effects*
  • Odontogenesis / radiation effects*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / radiotherapy
  • Tooth Abnormalities / etiology

Substances

  • Antineoplastic Agents