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Cytogenet Cell Genet. 1996;74(3):192-3.

FISH mapping of centromere protein C (CENPC) on human chromosome 4q31-->q21.

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  • 1Biology Department, Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong. boyxie@usthk.ust.hk


Centromere protein C (CENP-C), a human centromere autoantigen, is a component of the inner kinetochore plate. CENP-C is required for maintaining proper kinetochore size and a timely transition to anaphase. In this study using fluorescence in situ hybridization to metaphase chromosomes, the human CENP-C gene (CENPC) was mapped on chromosome 4, region q13-->q21.

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