Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Cell Biol. 1996 Dec;8(6):773-80.

The spindle assembly checkpoint.

Author information

  • 1Department of Physiology, Box 0444, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0444, USA. rudner@socrates.ucsf.edu

Abstract

The spindle assembly checkpoint monitors proper chromosome attachment to spindle microtubules and is conserved from yeast to humans. Checkpoint components reside on kinetochores of chromosomes and show changes in phosphorylation and localization as cells proceed through mitosis. Adaptation to prolonged checkpoint arrest can occur by inhibitory phosphorylation of Cdc2.

PMID:
8939672
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk