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Curr Biol. 1996 Oct 1;6(10):1226-9.

Intracellular signalling: the mad way to do it.

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  • 1Department of Growth and Development, University of California at San Francisco 94143-0640, USA.


A family of proteins has been identified that transduce a signal inside cells following binding of a TGF-beta family ligand to its cognate receptor. Like the prototype Drosophila protein Mad, many members of the family play key roles in developmental signalling.

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