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Curr Opin Neurobiol. 1996 Oct;6(5):679-87.

Therapeutic horizons for amyotrophic lateral sclerosis.

Author information

  • Department of Neurology, Johns Hopkins University, Baltimore, Maryland 21287, USA. jrothste@welchlink.welch.jhu.edu

Abstract

Recent theories on the pathogenesis of motor neuron disease and research on motor neuron injury have resulted in new putative therapies, which include treatment with various neurotrophic factors, antioxidants and anti-excitotoxicity agents. Clinical and preclinical studies have now provided the first agents that reproducibly alter the course of amyotrophic lateral sclerosis.

PMID:
8937834
[PubMed - indexed for MEDLINE]
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