Mutat Res. 1996 Oct 1;370(3-4):175-80.

Genotoxicity of lynoral (ethinyloestradiol, an oestrogen) in mouse bone marrow cells, in vivo.

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Department of Zoology, Goa University, India.

Abstract

The genotoxic effect of Lynoral (ethinyloestradiol, an oestrogen) was studied using mouse bone marrow cells treated in vivo, employing a chromosomal aberration assay and micronucleus test. The dose and time-yield effects of the sex hormonal drug were investigated. Lynoral failed to induce significant genetic damage in the bone marrow erythrocytes of mice, regarding chromosomal aberrations and micronuclei.

PMID:: 8917663; [PubMed - indexed for MEDLINE]

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Genotoxicity of lynoral (ethinyloestradiol, an oestrogen) in mouse bone marrow cells, in vivo.

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